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mesoestetic cosmelan® 2
mesoestetic cosmelan® 2
mesoestetic cosmelan® 2
mesoestetic cosmelan® 2
mesoestetic cosmelan® 2
mesoestetic cosmelan® 2

mesoestetic cosmelan® 2

Hyperpigmentation, Melasma, Sun Spots, and Age Spots
mesoestetic
R 6,635.00
VAT Included.

Target stubborn pigmentation at its source with mesoestetic cosmelan® 2 cream, the gold-standard professional-grade depigmenting treatment. Specially formulated to reduce melasma, sun-induced dark spots, post-inflammatory hyperpigmentation, and uneven tone, cosmelan® 2 works by directly regulating melanin production—the root cause of discolouration.

The advanced formula blends kojic acid to inhibit tyrosinase activity, azelaic acid for its brightening and anti-inflammatory effects, and arbutin and niacinamide to further unify skin tone and refine texture. Together, these actives progressively diminish visible pigmentation while supporting a clearer, more luminous complexion.

Designed as the essential home-care step of the renowned cosmelan® depigmentation method, cosmelan® 2 enhances and maintains the in-clinic mask results, but it can also be used as a standalone maintenance cream for long-term pigment control. With consistent use, visible improvements are typically seen within 2–3 months: skin looks brighter, texture feels smoother, and signs of premature ageing appear reduced.

Dermatologist-tested and available exclusively through authorised clinics, cosmelan® 2 is trusted worldwide for its proven efficacy. 

Please complete our cosmelan® 2 quiz before purchasing.

Size: 30g

Always apply to clean, dry skin on the entire face. Use a minimalist layer, light application is sufficient. Expect some redness, peeling, or sensitivity initially, these are normal and indicate activity. Always pair with supportive products: melan recovery balm (soothing) and melan 130+ pigment control SPF (sun protection).
  • Avoid using during pregnancy or on irritated skin.
  • Do not mix with other glycolic acid products or harsh actives unless instructed.
  • Strict daily photoprotection is mandatory, avoid sun exposure without SPF.

Kojic Acid serves as the cornerstone of this professional-grade depigmentation cream, working to effectively brighten skin and inhibit melanin production at its source. The formula is enhanced with Azelaic Acid, which provides complementary benefits through its anti-inflammatory properties and ability to regulate tyrosinase activity. This dermatologist-tested formulation delivers targeted action against hyperpigmentation whilst maintaining professional-grade efficacy in a gentle, clinic-approved treatment cream.

What's Inside

cosmelan® 2 questionnaire

Before starting your cosmelan® 2 journey, it’s important to check if this treatment is right for you. This short quiz will help us understand your skin type, concerns, and medical background, ensuring the product is used safely and effectively. The quiz only takes a few minutes to complete.

Complimentary Products
R 2,778.00

mesoestetic melan tran3x concentrate
R 1,910.00

mesoestetic melan tran3x gel cream
R 2,636.00

mesoestetic skinretin 0.3%
R 1,533.00

mesoestetic hydracream fusion
R 2,100.00

mesoestetic melan recovery
R 1,628.00

mesoestetic mesoprotech melan 130 pigment control
R 2,678.00

mesoestetic skin balance concentrate
R 1,533.00

mesoestetic hydratonic mist

FAQs

cosmelan® 2 is specially designed to address stubborn skin pigmentation such as melasma, age spots, sun spots, freckles, and post-inflammatory hyperpigmentation (PIH). It also helps tone skin texture and can support fine-line refinement as part of its regenerative action.

While the best results are achieved when cosmelan® 2 is used following the professional cosmelan® 1 mask, it can also be used as a standalone maintenance cream to control pigmentation and brighten your complexion long term.

Many users notice initial improvements like reduced dark spot intensity and enhanced glow within 2 to 4 weeks. Full-tone correction typically shows by 2–3 months with consistent, proper use.

Yes, but carefully. Because cosmelan® 2 contains potent actives like kojic and azelaic acid, those with sensitive or reactive skin should introduce it gradually and under professional guidance to minimise discomfort.

After Cosmelan® 1 mask: Start applying Cosmelan® 2 three times daily (morning, midday, evening) for the first month, then twice daily for the next two months, and finally once nightly from month 4 onward.

Without the mask: Begin with once nightly for a month, increase to twice-daily as tolerated, then reduce to nightly thereafter.

Always follow with melan recovery balm if needed for sensitivity, and mesoprotech melan 130+ SPF daily for sun protection.

Yes! Some initial flaking, light peeling, or temporary redness is common and signals the active ingredients working. Use hydrating, gentle after-care products and avoid physical or abrasive exfoliants during this phase.

Depending on your results and skin response, most people benefit from using cosmelan® 2 nightly for at least 4–6 months before transitioning to maintenance or repeating treatment.

Absolutely. strict sun protection with a broad-spectrum SPF daily is essential. Never skip sunscreen while using Cosmelan® 2 as UV exposure can undo progress and increase pigmentation.

It’s best used with a minimal, compatible routine, avoid using strong acids, aggressive actives, or other brighteners concurrently unless recommended by a professional.

If you develop persistent redness, burning, or discomfort, pause usage, use a gentle barrier-repair cream, and consult your skincare professional for adjustment. In rare cases, discontinuing may be necessary.