Start usage of the Vitamin A Propionate every other day for 2 weeks, progressing to daily application thereafter. Apply Vitamin A Propionate to clean skin at night only. Rub onto the skin until the white film disappears. This step facilitates deeper penetrating action leading to enhanced results. Mild irritation is normal, skip a few days and restart every other day until full tolerance level is achieved. If pregnant or breastfeeding, consult with your physician before use. DermaFix DermaShield SPF50 High Protection UVA/AUB sunscreen is essential for day use.